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29 mar 2023 · Vulval intraepithelial neoplasia (VIN) is a skin condition of the vulva. Find out about symptoms and treatment options.
- Living with Vulval Cancer
Cancer Research UK is a registered charity in England and...
- Symptoms of Vulval Cancer
Vulval intraepithelial neoplasia (VIN) VIN is a skin...
- Treatment for Vulval Cancer
Treatment for vulval cancer. Your treatment depends on a...
- What is Vulval Cancer
Vulval epithelial neoplasm (VIN) VIN is when abnormal cells...
- Stages and Grade of Vulval Cancer
is 2 cm or less in size; has only grown 1 mm or less into...
- Types of Vulval Cancer
Treatment includes surgery or a cream called imiquimod. This...
- Living with Vulval Cancer
24 lip 2023 · VIN 2 and VIN 3 are both considered high grade and have a higher risk of developing into cancer than low grade VIN. However, treatment can resolve VIN 2 and stop cancer from developing.
When occult invasion is not a concern, vulvar HSIL (VIN usual type) can be treated with excision, laser ablation, or topical imiquimod (off-label use). Women with vulvar HSIL (VIN usual type) are at risk of recurrent disease and vulvar cancer throughout their lifetimes.
Surgical excision and laser vaporisation may be equally effective treatments for uVIN, but about half of women will experience uVIN recurrence after either treatment. If cancer is suspected, despite a diagnosis of uVIN, surgical excision remains the treatment of choice.
7 maj 2022 · Activity, safety, and feasibility of cidofovir and imiquimod for treatment of vulval intraepithelial neoplasia (RT(3)VIN): a multicentre, open-label, randomised, phase 2 trial
1 lis 2020 · In a 2016 Cochrane review of medical and surgical interventions for the treatment of VIN, Lawrie et al. [33] recommended surgical excision as second-line therapy for patients who fail to respond to medical treatment. That said, first-line surgical excision (preferably superficial vulvectomy) of small, well-circumscribed lesions would probably ...
The immunomodulator, imiquimod, has been proposed as a medical alternative to surgical treatments. We performed a systematic review and meta-analysis to determine the efficacy of topical imiquimod on the treatment of high-grade vulvar intraepithelial neoplasia (VIN 2 and VIN 3).
