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When occult invasion is not a concern, vulvar HSIL (VIN usual type) can be treated with excision, laser ablation, or topical imiquimod (off-label use). Women with vulvar HSIL (VIN usual type) are at risk of recurrent disease and vulvar cancer throughout their lifetimes.
29 mar 2023 · Treatment options. Your treatment depends on: where the VIN is; your symptoms; the risk of it developing into cancer; Your doctor may suggest you have monitoring instead of treatment straight away. This is usual for low grade squamous intraepithelial lesion (LSIL) or VIN 1.
7 maj 2022 · Per-protocol topical 5% imiquimod treatment was found to be non-inferior to surgical intervention, including excision or laser vaporisation. After 6 months, complete clinical remission was successful in 80% of patients receiving per-protocol imiquimod treatment and 79% of patients undergoing surgery.
18 paź 2023 · The ideal treatment of VIN involves the complete destruction of the lesion, symptom improvement, and preservation of vulvar function. Treatment options include surgical, medical, or expectant management.
24 lip 2023 · However, treatment can resolve VIN 2 and stop cancer from developing. Surgery to remove the abnormal growth is the most common treatment. Additional options include cream, ointment, or...
25 lip 2024 · VIN and CIN are discussed separately. (See "Vulvar squamous intraepithelial lesions (vulvar intraepithelial neoplasia)" and "Cervical intraepithelial neoplasia: Management" and "Cervical intraepithelial neoplasia: Choosing excision versus ablation, and prognosis and follow-up after treatment".)
Treatment options for VIN include surgical excision, laser ablation, and topical treatment with imiquimod. In many women, a combination of these modalities is used. Retrospective data have shown that approximately 30% of patients treated for VIN develop recurrent disease, irrespective of treatment modality used.
