Search results
Treatment is recommended for all women with vulvar HSIL (VIN usual type). Because of the potential for occult invasion, wide local excision should be performed if cancer is suspected, even if biopsies show vulvar HSIL.
25 lip 2024 · CLASSIFICATION. VaIN is defined by the presence of squamous cell atypia without invasion. The disease is classified according to the depth of epithelial involvement: VaIN 1 and 2 involve the lower one-third and two-thirds of the epithelium, respectively (picture 1). VaIN 3 involves more than two-thirds of the epithelium.
20 cze 2022 · Medical treatment (imiquimod or cidofovir) can be considered for VHSIL. Recent studies favor an approach of using imiquimod in vulvar Paget’s disease. Surgery must take into consideration that the extension of the disease is usually wider than what is evident in the skin. A 2 cm margin is usually considered necessary.
3 lis 2023 · The purpose of this guideline update is to collate evidence and propose evidence-based guidelines for the management and diagnosis of adult patients with vulval carcinoma treated in the UK. Malignant melanoma may present via similar routes and will be discussed.
7 maj 2022 · Human papillomavirus (HPV)-induced vulvar high-grade squamous intraepithelial lesions (vHSIL), formerly known as usual-type vulvar intraepithelial neoplasia (VIN), has a cancer risk of approximately 10% and treatment is aimed at relieving symptoms and preventing progression towards cancer. 1 New therapeutic options have emerged to provide altern...
21 gru 2023 · First-line medical management is appropriate for women with biopsy-confirmed vulval high-grade squamous intraepithelial lesions who have been adequately counselled on the risk of occult invasive disease. Topical treatment should be undertaken in the context of a specialist clinic because it is not suitable for all patients.
1 lis 2020 · In a 2016 Cochrane review of medical and surgical interventions for the treatment of VIN, Lawrie et al. [33] recommended surgical excision as second-line therapy for patients who fail to respond to medical treatment. That said, first-line surgical excision (preferably superficial vulvectomy) of small, well-circumscribed lesions would probably ...
