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7 maj 2022 · It is the first study to prove non-inferiority of imiquimod compared to surgery and confirms the high efficacy of imiquimod as a first-line treatment option for vHSIL. We agree with Trutnovsky and colleagues 8 that identification of patients who benefit most from imiquimod is needed.
We now have better diagnostic tools. Ultrasound is readily available to most equine practitioners and can be helpful in determining the size of ligaments in the horse’s hip and pelvis, but nuclear scintigraphy (bone scan) is much more effective. This test involves injecting the horse with a radioactive material.
1 lis 2020 · Vulvar intraepithelial neoplasia (VIN) is classified into two entities: differentiated (dVIN) and vulvar high-grade squamous intraepithelial lesions (vH-SIL). dVIN is a premalignant lesion that develops on an existing vulvar lesion such as lichen sclerosus, while vH-SIL is associated with HPV infection.
24 lip 2023 · However, treatment can resolve VIN 2 and stop cancer from developing. Surgery to remove the abnormal growth is the most common treatment. Additional options include cream, ointment, or...
Classic VIN, like CIN, is associated with HPV and seen in younger women. May be multifocal, i.e. associated with cervical or vaginal lesions; multifocality has a strongly association with immunosuppression. Classic VIN is graded like cervical pre-cancerous lesions: VIN I. DDx: condyloma acuminatum. Uncommon. VIN II. Not common.
When occult invasion is not a concern, vulvar HSIL (VIN usual type) can be treated with excision, laser ablation, or topical imiquimod (off-label use). Women with vulvar HSIL (VIN usual type) are at risk of recurrent disease and vulvar cancer throughout their lifetimes.
29 mar 2023 · Vulval intraepithelial neoplasia (VIN) is a skin condition of the vulva. Find out about symptoms and treatment options.