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23 gru 2020 · The serotonin [5-hydroxytryptamine (5-HT)] system has been studied extensively in the etiology of anxiety and anxiety disorders, and the primary first-line pharmacotherapeutic agents for anxiety are serotonergic, including SSRIs, SNRIs, and azapirones like buspirone.
17 cze 2021 · As in generalized anxiety disorder, first-line (and second- and sometimes third-line) pharmacotherapy for panic disorder uses SRIs. The specific SSRIs that have FDA approval for panic disorder include fluoxetine, sertraline, and paroxetine (regular and controlled release).
17 cze 2021 · The serotonin [5-hydroxytryptamine (5-HT)] system has been studied extensively in the etiology of anxiety and anxiety disorders, and the primary first-line pharmacotherapeutic agents for anxiety are serotonergic, including SSRIs, SNRIs, and azapirones like buspirone.
Specifically, Selective Serotonin Reuptake Inhibitors (SSRIs), Selective Norepinephrine Reuptake Inhibitors (SNRIs), and benzodiazepines (BZs) have become the most commonly prescribed medications for GAD, due to their overall efficacy and relative tolerability.
SSRIs and SNRIs are effective in treating anxiety disorders. Higher doses of SSRIs within the therapeutic range are associated with greater treatment benefit, whereas higher doses of SNRIs are not.
The goals of this meta-analysis were to examine the efficacy of SSRIs and SNRIs for anxiety disorders examining (a) overall efficacy, (b) time course of treatment response, (c) individual pharmacological agent, (d) diagnostic indication, (e) dose, (f) tolerability, and (g) trial publication year.
16 cze 2022 · The specific aims of this study are as follows: (1) Evaluate the evidence of efficacy of FGAs and SGAs in anxiety disorders as an adjunctive treatment to SSRIs, serotonin norepinephrine reuptake inhibitors (SNRIs) and other non-antipsychotic medications; (2) Compare monotherapy with antipsychotics to first-line treatments for anxiety disorders i...