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Vayne Build with the highest win rate. Runes, items, and skill build in patch 14.20. Vayne build recommendations and guides.
R. Vayne with U.GG's best data for every build. The highest win rate Vayne build, from rune set to skill order to item path, for ADC. LoL Patch 14.20.
If you're looking for the best rune build for Vayne we've got you covered. Below you can find the best items and runes to build for Vayne, as determined by calculations of thousands of Plat+ League of Legends games.
Get the best Vayne builds, based on analysis of 10000+ matches in all regions and ranks. Climb in patch 14.20 with Vayne builds provided by Mobalytics!
You have the best primary rune on Vayne with Lethal Tempo and the highest defensive runes with Conditioning and Overgrowth. You will see me run a rune page similar to this almost 95% of the time since I heavily favor defensive runes.
x Gameplay. x Strategy. PROS. + Synergizes well with Kraken Slayer. + Meshes well with enchantress supports. + With the reset of her Final Hour she can go in and reset her R cooldown with kills making long fights a breeze with her. + Once you grab your Guinsoo's Rageblade.
Vayne Build with the highest win rate. Runes, items, and skill build in patch 14.20. Vayne build recommendations and guides.
