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Variola virus is one of the oldest viruses known to infect and cause diseases in humans. Variola virus was the etiological agent of smallpox, an epidemic throughout the human history. The process of variolation began in the seventeenth century and was widely practiced. Successful prophy-laxis was developed for smallpox.
Variola Virus Research (ACVVR), which was established in 1999, oversees all research using live variola virus, based on the World Health Assembly decisions contained in WHA49.10, WHA52.10 and WHA 55.15.
Since variola virus is a pathogen that is uniquely adapted to cause severe, widespread human illness, it is highly likely that it has evolved to specifically thwart an effective immune response to infection.
Variola Virus. Variola is a human-specific virus. Generally it can be readily distinguished from other orthopoxviruses capable of infecting man (vaccinia, cowpox, monkeypox) by the characteristic small white pocks produced on the chorioallantoic membrane of developing 12-to 15-day-old chick embryos and the ceiling temperature of growth. How ...
3 sie 2016 · This interactive module explores the diversity of viruses based on structure, genome type, host range, transmission mechanism, replication cycles, and vaccine availability.
This is a transmission electron microscopic (TEM) image of a tissue section containing variola virus particles, the pathogen responsible for causing smallpox in humans. These organisms display an internal, dumbbell-shaped structure that represents the viral core containing the viral DNA.
28 maj 2024 · Variola virus is one of the oldest viruses known to infect and cause diseases in humans. Variola virus was the etiological agent of smallpox, an epidemic throughout the human history. The process of variolation began in the seventeenth century and was widely practiced.
