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  1. 14 lut 2022 · Insulin resistance (IR) plays an important role in the pathophysiology of PCOS; therefore, its treatment may benefit women with the syndrome. The main drug used for IR management is metformin (MT). We aim to review the literature on the use of metformin in women with PCOS.

  2. 11 kwi 2021 · Clinical practice guidelines (CPGs) are key instruments to implement the practice of evidence-based medicine. We aimed to evaluate the methodological quality and variations in CPGs recommendations on the diagnosis and management of polycystic ovary syndrome (PCOS). Evidence Acquisition.

  3. Categories of PCOS guideline recommendations. The terms include ‘‘should’’, ‘‘could’’ and ‘‘should not’’, which are informed by the nature of the recommendation (evidence or consensus), the GRADE framework and the evidence quality and are independent descriptors reflecting GDG judgement.

  4. They concluded accordingly that metformin was an effective treatment to induce ovulation in PCOS patients and that it was justifiable to use it as a first-line treatment. However, they emphasized that it should be used in conjunction with a change in lifestyle.

  5. 11 kwi 2021 · Clinical practice guidelines (CPGs) are key instruments to implement the practice of evidence-based medicine. We aimed to evaluate the methodological quality and variations in CPGs recommendations on the diagnosis and management of polycystic ovary syndrome (PCOS).

  6. In 2018, the International Evidence-Based Guidelines for the Assessment and Management of PCOS were released to integrate best practices for the diagnosis and treatment of PCOS. Among these guidelines are updated recommendations for the use of metformin in patients with PCOS.

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