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  1. 16 wrz 2020 · Since 1994, metformin has been used as an insulin sensitizer for the treatment of polycystic ovary syndrome . Studies have shown that metformin can not only improve endocrine disorders in patients with PCOS but also regulate ovarian function and even reduce the weight of overweight women with PCOS .

  2. 14 lut 2022 · Metformin increases success rates and decreases complication rates when used as an adjunctive medication for ovulation induction during low complexity assisted reproduction treatments and during ovarian stimulation for in vitro fertilization in women with PCOS.

  3. They concluded accordingly that metformin was an effective treatment to induce ovulation in PCOS patients and that it was justifiable to use it as a first-line treatment. However, they emphasized that it should be used in conjunction with a change in lifestyle.

  4. first-line therapy for the treatment of women who are anovulatory and infertile with PCOS, metformin alone was significantly less effective than clomiphene citrate alone. 17,21 Furthermore, metformin does not improve metabolic

  5. 9 cze 2015 · BACKGROUND. Polycystic ovary syndrome (PCOS) is a common endocrine disorder with diverse reproductive and metabolic features. It is underpinned by insulin resistance that is exacerbated by obesity. Lifestyle modification is the first line treatment in PCOS, but it is associated with low adherence and sustainability.

  6. 23 paź 2003 · This is the first systematic review and meta-analysis of randomised controlled trials in the use of metformin in treating polycystic ovary syndrome. Where metformin is used as a sole agent, ovulation is achieved in 46% of recipients compared with 24% in the placebo arm (NNT = 4.4)

  7. 1 gru 2022 · The use of metformin in the management of PCOS will be reviewed here. The clinical manifestations, diagnosis, and other treatment options for PCOS are reviewed separately.

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