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5 lut 2021 · However, in patients with cardiovascular risk factors or cardiovascular disease combined therapy with metformin plus SGLT-2 or GLP-1RAs should be started as soon as possible. Metformin is also promoted as an effective medication for PCOS and used off-label in the management of T1DM, GDM and NAFLD.
- Role of Metformin in Polycystic Ovary Syndrome (PCOS)-Related ...
Many studies showed that metformin, when used to treat PCOS,...
- Role of metformin in the management of polycystic ovary syndrome
Several effects have been reported as related to metformin...
- Role of Metformin in Polycystic Ovary Syndrome (PCOS)-Related ...
31 sie 2023 · Many studies showed that metformin, when used to treat PCOS, significantly reduced serum androgen levels, improved insulin sensitivity, restored menstrual cyclicity, and was successful in triggering ovulation. As a result, metformin may be useful in treating PCOS-related infertility.
23 paź 2003 · Although modest, we believe that these benefits in variables known to be associated with adverse cardiovascular risk are further evidence to justify recommending the use of metformin as a first line treatment for anovulation in women with polycystic ovary syndrome.
12 sie 2021 · Metformin significantly decreased the risk of body weight gain and increased INSR expression in F1 female offspring in PCOS-IR rats, contributing to the improvement in obesity, hyperinsulinemia, and IR.
Among these guidelines are updated recommendations for the use of metformin in patients with PCOS. These recommendations advise that patients with PCOS and BMI≥25, impaired glucose tolerance, and/or adolescents age <18 should take metformin to prevent metabolic sequelae of PCOS (1).
Several effects have been reported as related to metformin in PCOS patients including restoring ovulation, reducing weight, reducing circulating androgen levels, reducing the risk of miscarriage and reducing the risk of gestational diabetes mellitus (GDM).
31 maj 2003 · We have reviewed the best available evidence on the use of metformin in women with PCOS (panel 2 presents a summary of findings). There was much variation in the patients examined and the methods of assessment used, but a consistent yet moderate improvement in ovarian function was established.
