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  1. 1 gru 2022 · The use of metformin in the management of PCOS will be reviewed here. The clinical manifestations, diagnosis, and other treatment options for PCOS are reviewed separately.

  2. 31 sie 2023 · Many studies showed that metformin, when used to treat PCOS, significantly reduced serum androgen levels, improved insulin sensitivity, restored menstrual cyclicity, and was successful in triggering ovulation. As a result, metformin may be useful in treating PCOS-related infertility.

  3. 22 kwi 2008 · Metformin is an agent that acts indirectly and modestly to improve ovulation and reduce long-term metabolic complications. The management of metabolic syndrome in women with PCOS must include tight blood pressure control, weight loss, diet modification, and possibly the use of agents for lipid modification.

  4. 23 paź 2003 · This is the first systematic review and meta-analysis of randomised controlled trials in the use of metformin in treating polycystic ovary syndrome. Where metformin is used as a sole agent, ovulation is achieved in 46% of recipients compared with 24% in the placebo arm (NNT = 4.4)

  5. 3 sty 2008 · Although metformin is increasingly used to treat patients with the polycystic ovary syndrome, therapy is guided in part by the results of randomized, controlled trials in populations...

  6. 14 lut 2022 · Insulin resistance (IR) plays an important role in the pathophysiology of PCOS; therefore, its treatment may benefit women with the syndrome. The main drug used for IR management is metformin (MT). We aim to review the literature on the use of metformin in women with PCOS.

  7. Abstract. Metformin is an old compound optimal for treatment of type 2 diabetes. Since when PCOS patients have been reported to have insulin resistance, metformin has been demonstrated to...