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  1. 15 kwi 2014 · Metformin is an effective ovulation induction agent for non-obese women with PCOS and offers some advantages over other first line treatments for anovulatory infertility such as clomiphene. For clomiphene-resistant women, metformin alone or in combination with clomiphene is an effective next step.

  2. 14 lut 2022 · Insulin resistance (IR) plays an important role in the pathophysiology of PCOS; therefore, its treatment may benefit women with the syndrome. The main drug used for IR management is metformin (MT). We aim to review the literature on the use of metformin in women with PCOS.

  3. 20 lis 2023 · The glucagon-like peptide-1 receptor agonists used in T2D can be considered as antiobesity treatment in PCOS together with active lifestyle intervention, ... Metformin should not be routinely used in pregnancy in PCOS but could be considered in some circumstances to reduce risk of preterm delivery or to limit excess gestational weight gain.

  4. They concluded accordingly that metformin was an effective treatment to induce ovulation in PCOS patients and that it was justifiable to use it as a first-line treatment. However, they emphasized that it should be used in conjunction with a change in lifestyle.

  5. 1 gru 2022 · The use of metformin in the management of PCOS will be reviewed here. The clinical manifestations, diagnosis, and other treatment options for PCOS are reviewed separately.

  6. 23 paź 2003 · This is the first systematic review and meta-analysis of randomised controlled trials in the use of metformin in treating polycystic ovary syndrome. Where metformin is used as a sole agent, ovulation is achieved in 46% of recipients compared with 24% in the placebo arm (NNT = 4.4)

  7. Among these guidelines are updated recommendations for the use of metformin in patients with PCOS. These recommendations advise that patients with PCOS and BMI≥25, impaired glucose tolerance, and/or adolescents age <18 should take metformin to prevent metabolic sequelae of PCOS (1).

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