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  1. Several effects have been reported as related to metformin in PCOS patients including restoring ovulation, reducing weight, reducing circulating androgen levels, reducing the risk of miscarriage and reducing the risk of gestational diabetes mellitus (GDM).

    • PubMed

      The classification of diabetes mellitus and the tests used...

  2. 14 lut 2022 · Metformin increases success rates and decreases complication rates when used as an adjunctive medication for ovulation induction during low complexity assisted reproduction treatments and during ovarian stimulation for in vitro fertilization in women with PCOS.

  3. 15 kwi 2014 · Metformin is an effective ovulation induction agent for non-obese women with PCOS and offers some advantages over other first line treatments for anovulatory infertility such as clomiphene. For clomiphene-resistant women, metformin alone or in combination with clomiphene is an effective next step.

  4. 1 gru 2022 · Interest in the use of metformin, an insulin-lowering drug, in PCOS increased when it was appreciated that insulin resistance played an important role in the pathophysiology of the disorder. However, we no longer recommend the use of metformin as a first-line therapy for any indication in women with PCOS.

  5. Women with PCOS usually have some of the following symptoms: • Irregular, infrequent or absent periods. • Difficulty becoming pregnant. • Increased testosterone levels resulting in abnormal hair growth, or scalp hair loss, acne, weight gain and insulin resistance.

  6. 20 lis 2023 · Metformin should not be routinely used in pregnancy in PCOS but could be considered in some circumstances to reduce risk of preterm delivery or to limit excess gestational weight gain. Metformin does not prevent miscarriage, gestational diabetes, hypertension, preeclampsia, or macrosomia in PCOS. 5, 20

  7. Insulin resistance (IR) plays an important role in the pathophysiology of PCOS; therefore, its treatment may benefit women with the syndrome. The main drug used for IR management is metformin (MT). We aim to review the literature on the use of metformin in women with PCOS.

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