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8 cze 2023 · Our key findings suggest the synergistic effect of hyperglycemia and SARS-CoV-2 spike protein in promoting endothelial dysfunction via activation of the ACE2-NOX axis, which may account for the exacerbation of COVID-19 infection among hyperglycemic patients.
9 lip 2022 · Acute deterioration of glucose regulation in a patient followed by BNT162b2 administration may be due to vaccine-induced autoimmune diabetes. Conclusion: Vaccination with BNT162b2 may trigger type 1 diabetes.
Herein, we report a case series of four newly diagnosed type 1 diabetes patients, possibly related to SARS-CoV-2 mRNA vaccination. The spike protein of SARS-CoV-2 interacts with host cells through Angiotensin-I converting enzyme-2 (ACE-2) receptors .
Antigen expression–localization following cell transfection with spike (S) protein mRNA-containing lipid nanoparticles (LNPs) used in anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines.
Trougakos and colleagues recently discussed the role of coronavirus disease 2019 (COVID-19) mRNA vaccine-induced spike (S) protein in adverse effects following vaccination [1].
4 sie 2023 · In this review, we have shown a small number of new-onset diabetes cases coincidently occurring soon after the COVID-19 vaccine, especially in those with genetic susceptibility. Despite being older, these patients had a similar phenotype to T1DM.
1 wrz 2024 · Multiple cases of postvaccination immune-related adverse events have been reported. We, hereby, present a patient who presented with new-onset type 1 diabetes mellitus (DM) after COVID-19 messenger RNA (mRNA) vaccination.