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5 lut 2024 · Statin drugs, also known as HMG-CoA reductase inhibitors, are a class of medications that block an early step in cholesterol production in the liver. Let’s break that down. Many people focus on dietary cholesterol, found in eggs, red meat and dairy, as the mechanism for having elevated cholesterol.
In the U.S., about 13.5 percent of women 45 to 64 take a statin medication to reduce their cholesterol, such as atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor,...
1 sty 2016 · Mean ages, 58–60 years, were similar across the statin groups. Most of these women were taking at least one concomitant medication. At baseline, mean LDL-C was 190 mg/dL (4.9 mmol/L), indicating that the women had substantial hypercholesterolemia.
27 maj 2023 · Not everyone who takes a statin will have side effects, but some people may be at a greater risk. Risk factors include: Taking multiple medicines to lower your cholesterol. Taking medicines that interact with statins. Being female. Having a smaller body frame. Being age 80 or older. Having kidney or liver disease. Drinking too much alcohol.
Another precaution when considering statins for elderly patients is the concern for drug interactions and the altered relationships involving drug metabolism and the aging body. Two main predictors of drug‐drug interactions include age (47% of patients age >75 years are on ≥5 drugs) and the severity and chronicity of disease.31, 32 ...
1 paź 2020 · Two large trials namely, PREVENTABLE (Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults) trial (National Heart, Lung, and Blood Institute grant U19AG065188) and an Australian randomized, placebo-controlled trial called STAREE (A Clinical Trial of Statin Therapy for Reducing Events in the Elderly) are ongoing. The ...
16 lip 2024 · Simvastatin was used primarily by prevalent users and atorvastatin by incident users. The majority was treated with moderate-intensity dosages and fewer women received high intensity treatment. Statins are widely prescribed in the elderly.
