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Indications for thyroid function testing. 2.1 Introduction. 2.2 Screening for thyroid dysfunction. 2.2 Surveillance of thyroid function. 2.3 Monitoring of thyroid function . Hypothyroidism. 3.1 Primary hypothyroidism . 3.2 Subclinical (mild) hypothyroidism. 3.3 Secondary hypothyroidism. 3.4 Congenital hypothyroidism.
There are six patterns of thyroid function tests. Low TSH, accompanied by raised free T4 and T3 concentrations (panel 2), indicates primary hyperthyroidism, most commonly caused by Graves’ disease, multinodular goitre, or toxic nodule. In these cases TSH should be undetectable and thyroid tissue should not be tender.
Tests Used to Detect Thyroid Dysfunction. Defining Ranges for Serum TSH. Individual’s range. • Much narrower than reference range. Lab reference range. • Defined by values in “normal” population. Target range. Goals for thyroxine treatment of specific conditions. Hypothyroidism: normalization of TSH within age-specific reference range.
1 wrz 2013 · The upper TSH reference limit has progressively declined over the last decade thanks to more sensitive TSH assays, more accurate thyroid antibody tests, and a more accurate selection of the reference population.
A Thyroid function test (TFT) commonly refers to the quantitation of thyroid stimulating hormone (TSH) and circulating thyroid hormones in serum to assess the ability of the thyroid gland to produce and regulate thyroid hormone production.
thyroid tests to remove current biases thereby allowing establishment of universal reference ranges that could apply to all methods and improve the clinical utility of thyroid testing. This chapter is designed to give an overview of the current status and limitations of the thyroid
The measurement of plasma TSH is the commonly accepted and most sensitive screening test for primary thyroid disorders, because the pituitary gland responds with great changes in its secretion, even to slight changes in the levels of free thyroid hormones.
