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Objective. To provide an overview of diagnostic and treatment strategies in pregnant patients with diabetes insipidus (DI). Methods. We review the changes in osmoregulation during normal pregnancy, characterize the various types of DI that can occur during pregnancy, and discuss the recommended management. Results.
- Diabetes Insipidus in Pregnancy: Etiology ... - Endocrine Practice
Increased awareness of diabetes insipidus in pregnancy may...
- Diabetes Insipidus in Pregnancy: Etiology ... - Endocrine Practice
This review focuses on a brief overview of osmoregulatory and vasopressin physiology in pregnancy and how this relates to the clinical presentation, pathophysiology, diagnosis and management of gestational DI, with comparisons to the other forms of DI during pregnancy.
1 wrz 2020 · Careful history, physical exam and diagnostic testing including urine and serum osmolality testing are required to identify this condition, as no gold standard test is available. For many forms of DI in pregnancy, namely GDI and CDI, dDAVP provides effective therapeutic response, given its resistance to placental vasopressinase degradation.
27 mar 2009 · Increased awareness of diabetes insipidus in pregnancy may lead to early diagnosis and appropriate treatment that will reduce the risks of maternal and fetal morbidity. Overall, growing experience with DDAVP has shown that it is a safe and effective treatment for diabetes insipidus caused by a variety of factors.
Management of central diabetes insipidus and transient diabetes insipidus of pregnancy can be achieved with 1-deamino-8-D-arginine vasopressin (desmopressin acetate) (DDAVP), a vasopressin analogue. Nephrogenic diabetes insipidus is typically resistant to both DDAVP and vasopressin and underlying causes should be addressed.
23 wrz 2015 · We highlight the need for clinical suspicion in pregnant women with typical DI symptoms, particularly in those with multiple pregnancies or liver dysfunction. The diagnostic challenges, which should rely on basal evaluations of serum and urine osmolality, rather than water deprivation test due to its risks in pregnancy.
18 paź 2023 · Gestational diabetes insipidus is a rare condition that can cause pregnant women to experience excessive thirst and frequent urination.
