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20 gru 2023 · Eosinophilia is a common feature of certain blood cancers, such as eosinophilic leukemia and Hodgkin lymphoma, as well as solid tumor cancers of the colon, lungs, breast, and others. This article describes the function of eosinophils and the conditions associated with eosinophilia.
29 sie 2024 · Elevated eosinophil levels can be detected through a simple blood test and are commonly associated with allergies and parasitic infections; however, they might occasionally be present in certain cancer cases.
9 gru 2022 · This review provides a case-based discussion of the differential diagnosis of HES, including the classification by clinical HES subtype. Treatment options are reviewed, including novel eosinophil-targeted agents recently approved for the treatment of HES and/or other eosinophil-associated disorders.
27 sie 2015 · Hypereosinophilic syndromes (HESs) are a group of rare disorders characterized by peripheral blood eosinophilia of 1.5 × 10 9 /L or higher and evidence of end organ manifestations attributable to the eosinophilia and not otherwise explained in the clinical setting.
5 gru 2015 · Conventional agents for the treatment of HES include corticosteroids, hydroxyurea, interferon α, and imatinib (the only agent FDA-approved for treatment of HES). 21 Numerous additional agents, including chlorambucil, vincristine, etoposide, cladribine, cytarabine, methotrexate, cyclosporine, alemtuzumab, and cyclophosphamide, have been used to ...
13 lis 2017 · Eosinophils are components of the immune microenvironment that modulates tumor initiation and progression. Although canonically associated with a detrimental role in allergic disorders, these cells can induce a protective immune response against helminthes, viral and bacterial pathogens.
15 wrz 2021 · Eosinophils are involved in a diverse range of processes. Human data suggest that eosinophils aid in body homeostasis; contribute to defense against parasitic, bacterial, and viral infections; are involved in cancer immunology; and have a pathologic role in eosinophilic diseases. •.
