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20 gru 2023 · Eosinophilia is a common feature of certain blood cancers, such as eosinophilic leukemia and Hodgkin lymphoma, as well as solid tumor cancers of the colon, lungs, breast, and others. This article describes the function of eosinophils and the conditions associated with eosinophilia.
20 lip 2021 · Eosinophilic leukemia is a cancer of the blood characterized by a high number of white blood cells, called eosinophils. Learn about symptoms, diagnosis, treatment, and outlook for this...
27 sie 2015 · Hypereosinophilic syndromes (HESs) are a group of rare disorders characterized by peripheral blood eosinophilia of 1.5 × 10 9 /L or higher and evidence of end organ manifestations attributable to the eosinophilia and not otherwise explained in the clinical setting.
13 lis 2017 · In clinical cancers, the presence of eosinophils at either tumor site or in peripheral blood is a favourable prognostic factor for most cancers, although evidence for a pro-tumorigenic role for eosinophils is reported (Table 2).
15 wrz 2021 · Eosinophils are involved in a diverse range of processes. Human data suggest that eosinophils aid in body homeostasis; contribute to defense against parasitic, bacterial, and viral infections; are involved in cancer immunology; and have a pathologic role in eosinophilic diseases. •.
30 lis 2018 · Although the recent development of agents that target eosinophils, including tyrosine kinase inhibitors and monoclonal antibodies, provides the possibility of more effective, less toxic approaches to treatment of HES, there are little available data to guide their use in these conditions.
9 gru 2022 · This review provides a case-based discussion of the differential diagnosis of HES, including the classification by clinical HES subtype. Treatment options are reviewed, including novel eosinophil-targeted agents recently approved for the treatment of HES and/or other eosinophil-associated disorders.
