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  1. 5 cze 2019 · Here, we report that loss of TG2 from bone marrow-derived cells sensitizes for high fat diet (HFD)-induced pathologies.

  2. 10 maj 2023 · Fortunately, you can lose belly fat with certain lifestyle changes. Here’s what you can do—and what you should not—to slim down your middle and improve your health. No extreme diets or marathon running required.

  3. 5 cze 2019 · Obesity is characterized by the accumulation of dead adipocytes and inflammatory macrophages in the adipose tissue leading to obesity-related metabolic syndrome. Here, we report that loss of TG2 from bone marrow-derived cells sensitizes for high fat diet (HFD)-induced pathologies.

  4. 14 cze 2024 · Transglutaminase 2 (TGM2), a multifunctional enzyme known to crosslink proteins important for GTPase, cell adhesion, and scaffold activities has been implicated in adipose tissue growth and functioning. The objective of this study was to investigate TGM2 effects in MetS in a diet-induced obese mouse model.

  5. 27 sie 2015 · Our study identifies TG2 as a novel negative regulator of adipogenesis. The prevalence of obesity is steadily increasing globally and is recognized as a major risk factor for diabetes, heart disease and certain cancers. 1, 2, 3 During excess energy intake adipose tissue expands to store extra lipids.

  6. 21 lis 2020 · F13A1 /FXIII-A transglutaminase has been linked to adipogenesis in cells and to obesity in humans and mice, however, its role and associated molecular pathways in human acquired excess weight...

  7. 4 sty 2022 · Fat deposited in your belly is biochemically different from fat elsewhere; it makes an inflammatory brew of bad chemicals that causes you to age faster than someone who has only minimal visceral fat. Studies show that visceral fat deep in the abdomen is the most important health predictor in women. 1.

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