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  1. For term infants, specific indications are serum bilirubin ≥ 20 mg/dL (≥ 342 micromol/L) at 24 to 48 hours or ≥ 25 mg/dL (≥ 428 micromol/L) at > 48 hours and failure of phototherapy to result in a 1- to 2-mg/dL (17- to 34-micromol/L) decrease within 4 to 6 hours of initiation or at the first clinical signs of kernicterus regardless of ...

  2. 2022 AAP Hyperbilirubinemia Guidelines What's new? Highlights the challenge of identifying G6PD deficiency in infants. Bases follow-up testing on the difference between bilirubin level and the phototherapy threshold. No more risk zones! Raises thresholds for phototherapy and exchange transfusion.

  3. 5 sie 2022 · Use total serum bilirubin concentrations; do not subtract direct bilirubin from the total serum bilirubin. In rare cases of severe hyperbilirubinemia in which the direct-reacting or conjugated bilirubin exceeds 50% of the TSB, consult an expert.

  4. 31 paź 2023 · This guideline covers diagnosing and treating jaundice, which is caused by increased levels of bilirubin in the blood, in newborn babies (neonates). It aims to help detect or prevent very high levels of bilirubin, which can be harmful if not treated.

  5. Neonatal hyperbilirubinemia is a common clinical problem encountered during the neonatal period, especially in the first week of life (2, 3). Nearly 8% to 11% of neonates develop hyperbilirubinemia. When the total serum bilirubin (TSB ... Phototherapy and exchange blood transfusion are recommended when a level is greater than 0.5% and 1% ...

  6. 1 sty 2020 · According to the Clinical Practice Guideline of American Academy of Pediatrics (AAP), the total serum bilirubin or transcutaneous bilirubin level should be measured in each infant in the first 24 hours of life, to reduce the incidence of severe hyperbilirubinemia However, recent studies have shown that the concentration of serum unconjugated ...

  7. 17 lis 2014 · The crux of hyperbilirubinemia and bilirubin-induced neurotoxicity risk evaluation remains the measurement of total serum bilirubin interpreted in an hour-specific fashion, Citation 17, Citation 18 and the mainstays of intervention are phototherapy and exchange transfusion.

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