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Postnatal rubella (German measles) is a generally mild, self-limited illness characterized by rash, lymphadenopathy, and low-grade fever. However, congenital rubella may cause a number of anomalies, depending on the organ system involved and gestational age.
Togaviruses are small, single-strand positive-sense envelope-bearing (hence “toga”) RNA viruses. One member of the Togavirus family is the nonarboviral rubella-causing Rubivirus. In another genus are the alphaviruses.
Congenital rubella syndrome (CRS) is the term used to describe the group of congenital abnormalities that occur in a child as a result of rubella infection of mother during gestation. The clinical features can be transient, self-limiting, or permanent, and some features may not manifest until adolescence or adulthood (called “late ...
Rubella virus is an enveloped RNA virus with a single antigenic type that does not cross-react with other togaviruses. Rubella virus can be grown in several common laboratory cell lines. Sequencing of the ∼10 000 nucleotide long, single-stranded rubella genome has been completed.
Togaviruses are important veterinary pathogens, and are transmitted via mosquitoes. Some of them are zoonotic viruses, including Venezuelan equine encephalitis virus (VEEV). Rubella virus is the only member of togavirus family that causes significant disease in human—German measles.
Rubella (German measles) is a common mild disease characterized by a rash. It affects children and adolescents worldwide and can also affect young adults. When rubella virus infects susceptible women early in pregnancy, it may be transmitted to the fetus and may cause birth defects.
This Osmosis High-Yield Note provides an overview of Togaviruses essentials. All Osmosis Notes are clearly laid-out and contain striking images, tables, and diagrams to help visual learners understand complex topics quickly and efficiently.