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  1. • All premature infants on oxygen should have routine pulse oximetry at every visit. • The only additional laboratory study to order is an overnight pulse oximetry study if the infant meets criteria. THERAPEUTICS . Oxygen: Titrate oxygen to goal of oxygen saturation greater than 95% . PARENT | CAREGIVER EDUCATION • Expected clinical course

  2. As soon as a baby requires oxygen, then the 88-93% limits must be applied. Where to place the oxygen saturation probe? The best place is on the right hand/wrist, which will give a pre-ductal reading of oxygen saturation – this is the blood that goes to the brain and eyes.

  3. Apart from titration of oxygen therapy, this guideline document also addresses the need of humidification and various technological choices in monitoring and titrating oxygen therapy. This guideline applies to neonates who require oxygen or respiratory support in the first few weeks after birth.

  4. Oxygen concentration should be set to achieve a PaO2 of 50 to 70 mm Hg in preterm infants and 50 to 80 mm Hg in term infants or an oxygen saturation of 90 to 94% in preterm infants and 92 to 96% in term infants.

  5. 23 sie 2022 · Oxygen Saturation Histogram for babies on respiratory support. Arbitrary cut off of ≥20% below 90% Spo2 and ≥20% of time above 95% as sub optimal. This should be considered along with other cardio-respiratory parameters: PCO2, work of breathing and apneic episodes. No evidence/extrapolated data.

  6. Clinicians should ideally aim to titrate supplemental oxygen therapy to maximize the amount of time spent in the appropriate target oxygen saturation range, taking care to avoid prolonged periods of either hypoxemia or hyperoxemia as a trade-off.

  7. Oxygen saturations should be targeted within the range of 91-95%, when receiving oxygen therapy, in both preterm and term neonates. Fi0 2 is one of several determinants of arterial oxygenation provided by supplemental oxygen therapy.

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