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14 maj 2023 · The postulate of the 3Rs consists of: reducing, refining, and replacing animals in research laboratories (Ranganatha and Kuppast, 2012; Zurlo et al., 1996). Since that time, several ethical ...
16 maj 2022 · At the international level, SNP3Rs collaborates closely with the Czech 3Rs-Centre, located at the National Institute of Public Health (NIPH) in Prague. In 2020, SNP3Rs joined the European network of Three Rs centres, affiliated to the European Society for Alternatives to Animal Testing (EUSAAT).
WHO Chron. 1985; 39 (2):51–56. [Google Scholar] Stokes WS, Jensen DJ. Guidelines for Institutional Animal Care and Use Committees: consideration of alternatives. Contemp Top Lab Anim Sci. 1995 May; 34 (3):51–60. [Google Scholar] Festing MF. The scope for improving the design of laboratory animal experiments.
The 3Rs of Animal Research are Reduction, Refinement, and Replacement. The 3Rs were conceptualized by William Russell and Rex Burch in The Principles of Humane Experimental Technique, first published in 1959.
Abstract. In the 60th year since the publication of The Principles of Humane Experimental Technique by W.M.S. Russell and R.L. Burch, we visited the W.M.S. and Claire Russell Archive at the University of Nottingham to discover, or confirm, answers to certain questions: the origins of the UFAW project which led to its writing; the relationship ...
1 kwi 2019 · Abstract. Despite improvements in heart failure therapies, hospitalization readmission rates remain high. Nationally, increasing attention has been directed toward reducing readmission rates and thus identifying patients with the highest risk for readmission.
All tissues and organs can be classified according to their ability to repair and regenerate during adult homeostasis and after injury. Some exhibit a high rate of constant cell turnover, while others, such as the lung, exhibit only low-level cell regeneration during normal adult homeostasis but hav ….