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19 maj 2021 · At concentrations of 2.7–4.94 mg/kg body weight/day, alpha-lipoic acid is well tolerated and posed no health risks to dogs while providing improved antioxidant capacity. This review thereby supports the utility of alpha-lipoic acid as an effective nutritive additive in dog food.
22 sty 2021 · The daily consumption of dry dog food containing up to 300 ppm a-LA for 6 months did not have any adverse effects on physical appearance, body weight, food intake, serum biochemistry or CBC of healthy adult dogs.
The most common side effects of supplementation with oral lipoic acid were allergic reactions of the skin, such as rashes, itching and hives [40,41]. Nausea, vomiting, abdominal pain, diarrhea and vertigo were also occasionally reported. In one study, the incidence of nausea, vomiting, and vertigo was found to be dose dependent .
22 sty 2021 · This study was designed to determine the effect of alpha-lipoic acid on the glutathione status in healthy adult dogs. Following a 15 month baseline period during which dogs were fed a food containing no alpha-lipoic acid, dogs were randomly allocated into four groups.
Alpha Lipoic Acid, also known as ALA, is a human dietary supplement used in the management of diabetes. While more toxic in cats, ALA can be dangerous if ingested by any pet. Signs and symptoms of toxicity: Toxicity may be seen within 30 minutes or it may take up to several hours to develop.
1 sty 2013 · This study shows that long-term lipoic acid intake of up to 52.9 mg/kg body/day (3000 ppm diet) does not have any negative effects on the health of adult dogs.
published the acute oral LD50 for dogs to be 400-500 mg/kg body weight (Packer et al. 1995). A recent case report of two dogs showed that clinical signs of acute toxicity and death can occur at estimated single oral doses of 190 mg/kg and 210 mg/kg body weight, respectively (Loftin and Herold 2009). This current study was designed to
