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Mother is a boss added in The Binding of Isaac: Repentance and the only boss of the second floor of the Corpse, as well as the final boss of Ending 21. Upon entering the boss room in Corpse II, the room is empty except for a hole in its center.
Gehenna Bosses. Debut Bosses in Rebirth. Mom is the boss that appears on the second floor of Chapter 3 (Depths, Necropolis, Dank Depths). She is the initial final boss of the game, and defeating her for the first time unlocks both the Epilogue ending and Chapter 4 (Womb).
If Isaac uses the Black Rune to absorb items from a room with choice pedestals, it will only absorb one item, and the other item vanishes as if Isaac took it. The Black Rune can be used to absorb Knife Piece 1 if Mother isn't the goal of the run.
Mom is the main antagonist of The Binding of Isaac and can always be found as the Boss in the second level of Chapter 3 (The Depths and Necropolis) and is the final boss for the game's prologue. The mother of Isaac, she is a delusional woman who believes that the hallucination she hears telling her to murder her son is the voice of God.
I'm probably missing a few. As for phase 2 be sure to not get hit by the lazer at the start, you can avoid it by going to the sides of the room, and the hardest attack for that phase is a bunch of little tear strings that get shot out as mother does a spin, but those don't home in on you.
The charge always starts at the top on whatever side you're closer to and always ends with a slam in the center. Mother can block the bullets of the puke ball, and she's very wide. Get her to spit it vertically, on whatever side has the most room, then move to the other side of her.
Mom is voiced by Carla Kihlstedt. The battle theme for this boss is "Matricide", a term for the killing of one's own mother. Mom appeared in the original The Binding of Isaac. In the original, Mom's voice was provided by Michelle Schroeder-Lowrey, [1] an associate of Jordan Fehr, the sound designer.
