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2 wrz 2024 · Researchers at The University of Texas MD Anderson Cancer Center have shown that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.
24 sty 2024 · In an in vivo study conducted in mice, telomerase gene therapy using an adeno-associated virus to express TERT led to significant health improvements and reduced aging markers without elevating cancer incidence.
12 mar 2023 · Key takeaways. Telomeres are combinations of DNA and protein at the end of a chromosome that get shorter as you get older. Some research has linked shorter telomere length to an increased risk of...
Here, we determined whether APOE-ε4 status impacts leukocyte telomere length (TL) and the rate of cellular senescence in healthy mid-life women and, further, whether hormone replacement therapy (HT) modifies this association.
1 lis 2023 · The link between telomere dysfunction, hallmarks of aging and incidence of age-related diseases has spawned interest in telomerase recovery therapy as a potential anti-aging strategy.
21 cze 2024 · Researchers have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in ...
14 sty 2021 · Such an elemental role encourages the development and rigorous testing of telomerase activators for treatment of aging and age-associated diseases as well as assessment of efficient telomerase inhibitors for treatment of advanced cancers.