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Rapid communication: TB antigen-based skin tests for the diagnosis of TB infection •The TBST class is defined as skin tests for the detection of TB infection that use Mtb specific antigens (ESAT6 and CFP10) •In 2021, WHO commissioned a systematic review of published and unpublished data on this new
14 maj 2024 · If the first TB skin test result is negative, a second TB skin test should be done 1 to 3 weeks later. If the second TB skin test result is positive, it is probably a boosted reaction. Based on this second test result, the person should be classified as previously infected.
1 gru 2021 · Children with adequate anti-TB treatment need not be retested. The test of infection (either TST or IGRA) remains positive after adequate treatment and should not be used as a test of cure or as surveillance for emergence of TB disease.
Treatment of DR-TB in children – use of bdq & dlm in children. In children with MDR/RR-TB aged below 6 years, an all-oral treatment regimen containing bedaquiline may be used. In children with MDR/RR-TB aged below 3 years, delamanid may be used as part of longer regimens.
In 1996, the American Academy of Pediatrics (AAP) recommended targeted tuberculin skin testing (TST) of children while discouraging routine TST of children without risk factors for tuberculosis (TB). Recent studies have provided evidence in support of the targeted TST and recommendations that favor risk assessment over universal screening with TST.
Existing diagnostic tests for TB in children have shortcomings, and the full range of tests - including bacteriological culture and tuberculin skin testing (TST) - is often unavailable in settings where the majority of TB cases occur.
In this stage, the initial test of infection (either a tuberculin skin test [TST] or interferon gamma [IFN-γ] release assay [IGRA]) is negative, the chest radiograph is normal, and the child lacks signs or symptoms of disease.
