Search results
17 wrz 2020 · Tamoxifen (TAM) inducible Cre recombinase system is an essential tool to study gene function when early ablation or overexpression can cause developmental defects or embryonic lethality. However, there remains a lack of consensus on the optimal route and dosage of TAM administration in vivo.
- Refined protocols of tamoxifen injection for inducible DNA ...
Inducible DNA recombination of floxed alleles in vivo by...
- Tamoxifen - PubMed
Tamoxifen is indicated for the treatment of breast cancer in...
- Tamoxifen - StatPearls - NCBI Bookshelf - National Center for ...
This activity outlines the indications, mechanism of action,...
- Refined protocols of tamoxifen injection for inducible DNA ...
12 kwi 2018 · Inducible DNA recombination of floxed alleles in vivo by liver metabolites of tamoxifen (TAM) is an important tool to study gene functions. Here, we describe protocols for optimal DNA recombination in astrocytes, based on the GLAST-Cre ERT2 /loxP system.
10 kwi 2023 · Tamoxifen is indicated for the treatment of breast cancer in a variety of settings. It should be noted that evidence suggests that patients with estrogen receptor-positive tumors are more likely to benefit from tamoxifen.
10 kwi 2023 · This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, toxicity, and monitoring, of tamoxifen, so providers can direct patient therapy in treating indicated disorders as part of the interprofessional team.
1 sty 2018 · Tamoxifen is considered a pioneering drug due to its ubiquitous use in both treatment and chemoprevention of breast cancer and also for research addressing novel selective estrogen receptor modulators (SERMs). Tamoxifen is cost effective, lifesaving, and devoid of major side effects in the majority of patients.
Abstract. Background: Four previously published randomised clinical trials have shown that tamoxifen can reduce the risk of breast cancer in healthy women at increased risk of breast cancer in the first 10 years of follow-up.
12 kwi 2018 · 1 Altmetric. Metrics. Abstract. Inducible DNA recombination of floxed alleles in vivo by liver metabolites of tamoxifen (TAM) is an important tool to study gene functions. Here, we describe...
