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10 kwi 2023 · Tamoxifen is a selective estrogen receptor modulator (SERM) medication used to treat breast cancer in men and women and as a prophylactic agent against breast cancer in women.
10 lut 2023 · Tamoxifen became the treatment of first choice for virtually all clinical situations but the advent of well-tolerated third-generation aromatase inhibitors and selective oestrogen receptor...
14 mar 2023 · We conducted a randomized phase III trial in women with excised atypical ductal hyperplasia (ADH), lobular carcinoma in situ (LCIS), and ductal carcinoma in situ (DCIS), showing that tamoxifen 5 mg once daily given for 3 years halved recurrence without exceeding adverse events, resulting in a more favorable cost-benefit profile than 20 mg once ...
13 lip 2018 · Our analysis shows that monitoring serum concentrations of endoxifen after 3 months and accordingly escalating the dose of adjuvant tamoxifen in women with breast cancer who have serum concentrations lower than 5.97 ng/mL will likely be cost effective.
1 sty 2018 · Tamoxifen is considered a pioneering drug due to its ubiquitous use in both treatment and chemoprevention of breast cancer and also for research addressing novel selective estrogen receptor modulators (SERMs). Tamoxifen is cost effective, lifesaving, and devoid of major side effects in the majority of patients.
10 kwi 2023 · Publication types. Tamoxifen is indicated for the treatment of breast cancer in a variety of settings. It should be noted that evidence suggests that patients with estrogen receptor-positive tumors are more likely to benefit from tamoxifen. FDA-approved Indications include treatment of breast cancer in both females an ….
4 sie 2017 · Patients with ER-positive breast cancer, regardless of high or low 70-gene risk classification, receive significant survival benefit lasting over 10 years from adjuvant tamoxifen therapy, even when given for a relatively short duration.
