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Prendiville and colleagues 21 compared a cohort of 20 TCV cases (undefined proportion) with a historic comparison (n = 1355) and concluded that tall cell histologic findings did not predict recurrence or survival, but that extrathyroid extension and higher stage were prognostic.
In one study, Ganly et al found that PTC cases containing 30%-49% tall cells and cases containing ≥ 50% tall cells have similar clinicopathologic features and survival, but both of them bear more aggressive features and poorer prognosis than PTC cases with < 30% tall cells. Therefore, they recommended the threshold of tall cells in the tumor ...
28 gru 2020 · Conclusions: Tall cell papillary carcinoma is the most frequent aggressive variant of papillary thyroid cancer. Tall cell histology represents an independent poor prognostic factor compared to conventional variants.
A comparison of the clinicopathological features and prognoses of the classical and the tall cell variant of papillary thyroid cancer: a meta-analysis. Oncotarget. 2017 Jan 24;8(4):6222-6232. doi: 10.18632/oncotarget.14055.
16 lip 2018 · The subtype of the papillary thyroid carcinoma tall-cell variant has a worse prognosis than does the conventional papillary type (papillary thyroid carcinoma). The new World Health Organization 2017 classification defines a tall-cell variant as a tumour consisting of over 30% of cells that are two or three times as tall as they are wide.
26 lip 2010 · A total of 131 cases of tall cell variant papillary thyroid cancer were reviewed. The combined odds ratio of recurrence for TCV compared to UV is 4.50 with a 95% confidence interval from 2.90 to 6.99.
5 kwi 2023 · This is the largest mono-institutional study addressing the debated issue about the impact of tall-cell areas on papillary thyroid carcinoma (PTC) prognosis correlated with patient age.
