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1. pubmed.ncbi.nlm.nih.gov › 28295481Effects of taking tadalafil 5 mg once daily on erectile function...

   pubmed.ncbi.nlm.nih.gov › 28295481

   We aimed to evaluate the efficacy of tadalafil 5 mg once-daily treatment on testosterone levels in patients with erectile dysfunction (ED) accompanied by the metabolic syndrome. A total of 40 men with metabolic syndrome were evaluated for ED in this study.

2. drc.bmj.com › content › 8Correcting imbalance of sex hormones by a phosphodiesterase 5...

   drc.bmj.com › content › 8

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   Twelve-week treatment with tadalafil increased total and free testosterone levels and decreased estradiol levels in both rat types (figure 1D-F). LH levels were significantly higher in LETO rats at 48 weeks compared with 36 weeks .

3. pubmed.ncbi.nlm.nih.gov › 24726311Impact of low testosterone on response to treatment with...

   pubmed.ncbi.nlm.nih.gov › 24726311

   In men with partial response to a PRN PDE5I, tadalafil 5 mg once daily significantly improved ED and sexual function vs placebo irrespective of testosterone levels.

4. www.ncbi.nlm.nih.gov › pmc › articlesRole of application of tadalafil 5 mg once-daily (≥6 months) in...

   www.ncbi.nlm.nih.gov › pmc › articles

   30 gru 2019 · Several clinical studies have evaluated the safety and efficacy of tadalafil dosed once daily in patients with ED. Compared with taking on demand, it can eliminate the embarrassment of taking medication before intercourse, increase male confidence, avoid psychological barriers between husband and wife, especially for patients with severe ED.

5. www.sciencedirect.com › science › articleImpact of Low Testosterone on Response to Treatment With...

   www.sciencedirect.com › science › article

   1 cze 2014 · In men with partial response to a PRN PDE5I, tadalafil 5 mg once daily significantly improved ED and sexual function vs placebo irrespective of testosterone levels. Testosterone plays a key role in the modulation of erectile function.

6. pubmed.ncbi.nlm.nih.gov › 32882122[Effects of Tadalafil 5 mg Once-Daily on Serum Testosterone Level...

   pubmed.ncbi.nlm.nih.gov › 32882122

   Five mg tadalafil was administered once-daily to 48 patients for 6 months. Their International Prostatic Symptoms Score (IPSS), Overactive Bladder Symptoms Score (OABSS), Sexual Health Inventory for Men (SHIM), post-voided residual (PVR) volume, free testosterone (FT) level, prostate-specific antige ….

7. www.nature.com › articles › s41443/021/00512-wTestosterone replacement therapy and erectile dysfunction -...

   www.nature.com › articles › s41443/021/00512-w

   8 sty 2022 · When using tadalafil as the PDE5i in combination therapy, the daily dosage might be more efficacious than on-demand dosing.