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4 sty 2022 · This Review discusses the emerging applications of RNA devices in biomedical research and biomanufacturing, as well as progress in creating new ligand sensors and new mechanisms of action...
In this Review, we discuss current applications of RNA devices spanning research, biomanufacturing and clinical uses. We then review advances in expanding analyte sensing and mechanisms of action with engineered RNA.
4 sty 2022 · RNA devices spanning research, biomanufacturing and clinical uses. We then review advances in expanding ana-lyte sensing and mechanisms of action with engineered RNA.
19 maj 2017 · However, the number of available devices is limited due to the difficulty in the detection of endogenous proteins within a cell. Here, we show a strategy to construct synthetic mRNA devices that detect endogenous proteins in living cells, control translation and distinguish cell types.
1 cze 2020 · Synthetic RNA molecules expressed within cells can be optimized for a variety of tasks that include control of gene expression and organization of small molecules and proteins. Here, we review recent research advances that exploit RNA structure for synthetic biology applications.
23 sty 2023 · Here, we review both existing and emerging DNA synthesis technologies, with an emphasis on methodologies developed in industry as a means to accelerate the supply of long synthetic DNA.
4 sty 2022 · Herein, we present a generalizable and versatile strategy to engineer synthetic DNA ligand-binding devices that can be programmed to load and release a specific ligand at a defined...
