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4 sty 2022 · Nature Reviews Genetics - Synthetic RNA devices integrate sensing, processing and actuation of signals into defined, programmable functions to control cell behaviour. This Review discusses...
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4 sty 2022 · Leveraging the dependence of the CRISPR system on a guide RNA (gRNA), researchers designed a control system that incorporates small molecule-responsive aptamers into the 3′ region of the gRNA...
17 sty 2022 · Synthetic DNA is the basis for promising technologies in data storage, barcoding, computing 62 and sercurity. In this review, the authors provide an overview of the field and its future.
RNA devices integrate cellular information sensing, processing and actuation of specific signals into defined functions and have yielded programmable biological systems and novel therapeutics of increasing sophistication.
1 cze 2020 · We review recent advances in the design and expression of synthetic RNA sequences inside cells, to regulate gene expression and to achieve spatial localization of components.
4 sty 2022 · Synthetic RNA devices integrate sensing, processing and actuation of signals into defined, programmable functions to control cell behaviour. This Review discusses the emerging applications of RNA devices in biomedical research and biomanufacturing, as well as progress in creating new ligand sensors and new mechanisms of action with engineered RNAs.
16 wrz 2011 · We will review the rapidly growing field of RNA synthetic biology as it transitions from the molecular design of RNA-based genetic parts and devices to the implementation of these elements in genetic systems for programming complex biological behaviors.