Search results
4 sty 2022 · Nature Reviews Genetics - Synthetic RNA devices integrate sensing, processing and actuation of signals into defined, programmable functions to control cell behaviour. This Review discusses...
RNA devices integrate cellular information sensing, processing and actuation of specific signals into defined functions and have yielded programmable biological systems and novel therapeutics of increasing sophistication.
23 godz. temu · Abstract. Synthetic genomics seeks to design and construct entire genomes to mechanistically dissect fundamental questions of genome function and to engineer organisms for diverse applications ...
1 cze 2020 · Synthetic RNA molecules expressed within cells can be optimized for a variety of tasks that include control of gene expression and organization of small molecules and proteins. Here, we review recent research advances that exploit RNA structure for synthetic biology applications.
4 sty 2022 · Components of synthetic RNA devices. A major research focus in synthetic biology is the devel-opment of modular frameworks for constructing geneti-cally encoded devices and engineered...
The synthesis of synthetic DNA is often referred to generically as “gene synthesis,” which specifically is the synthesis of gene-length pieces of DNA (250–2000 bp) directly from single-stranded synthetic DNA oligonucleotides.
19 maj 2017 · However, the number of available devices is limited due to the difficulty in the detection of endogenous proteins within a cell. Here, we show a strategy to construct synthetic mRNA devices that detect endogenous proteins in living cells, control translation and distinguish cell types.
