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4 sty 2022 · Abstract. The versatility of RNA in sensing and interacting with small molecules, proteins and other nucleic acids while encoding genetic instructions for protein translation makes it a...
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RNA devices integrate cellular information sensing, processing and actuation of specific signals into defined functions and have yielded programmable biological systems and novel therapeutics of increasing sophistication.
17 sty 2022 · Synthetic DNA is the basis for promising technologies in data storage, barcoding, computing 62 and sercurity. In this review, the authors provide an overview of the field and its future.
1 cze 2020 · Synthetic RNA molecules expressed within cells can be optimized for a variety of tasks that include control of gene expression and organization of small molecules and proteins. Here, we review recent research advances that exploit RNA structure for synthetic biology applications.
16 wrz 2011 · We will review the rapidly growing field of RNA synthetic biology as it transitions from the molecular design of RNA-based genetic parts and devices to the implementation of these elements in genetic systems for programming complex biological behaviors.
4 sty 2022 · Leveraging the dependence of the CRISPR system on a guide RNA (gRNA), researchers designed a control system that incorporates small molecule-responsive aptamers into the 3′ region of the gRNA...
The synthesis of synthetic DNA is often referred to generically as “gene synthesis,” which specifically is the synthesis of gene-length pieces of DNA (250–2000 bp) directly from single-stranded synthetic DNA oligonucleotides.
