Search results
4 sty 2022 · Nature Reviews Genetics - Synthetic RNA devices integrate sensing, processing and actuation of signals into defined, programmable functions to control cell behaviour. This Review discusses...
- Full Size Image
Full Size Image - Engineering synthetic RNA devices for cell...
- Metrics
Metrics - Engineering synthetic RNA devices for cell control...
- View Author Publications
View Author Publications - Engineering synthetic RNA devices...
- RSS Feed
Nature Reviews Genetics is an invaluable source of...
- Conferences
You can meet the editors of Nature Reviews Genetics (Linda...
- Posters
Double-stranded RNA (dsRNA) molecules can be used to induce...
- Full Size Image
19 maj 2017 · However, the number of available devices is limited due to the difficulty in the detection of endogenous proteins within a cell. Here, we show a strategy to construct synthetic mRNA devices that detect endogenous proteins in living cells, control translation and distinguish cell types.
19 lis 2018 · In this study, we construct a set of RNA-based logic circuits with RBPs that detect multiple miRNA inputs and regulate the output protein expression (Fig. 1a). We create five logic gates (AND,...
23 wrz 2019 · Synthetic RNA-based genetic devices dynamically control a wide range of gene-regulatory processes across diverse cell types. However, the limited throughput of quantitative assays in...
RNA devices integrate cellular information sensing, processing and actuation of specific signals into defined functions and have yielded programmable biological systems and novel therapeutics of increasing sophistication.
1 cze 2020 · Synthetic RNA molecules expressed within cells can be optimized for a variety of tasks that include control of gene expression and organization of small molecules and proteins. Here, we review recent research advances that exploit RNA structure for synthetic biology applications.
16 wrz 2011 · Abstract. RNA molecules play diverse functional roles in natural biological systems. There has been growing interest in designing synthetic RNA counterparts for programming biological function.
