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21 cze 2024 · Sulforaphane (SFN), as a member of the isothiocyanates (ITCs) family, which is the hydrolysis product of glucosinolates (GLs), has been shown to have significant preventive and therapeutic cancer effects in different human cancers.
23 lip 2017 · A double-blinded, randomized, placebo-controlled clinical trial that involved 78 patients with biochemical recurrence of prostate cancer after radical prostatectomy used a daily oral administration of 60 mg of stabilized free SFN for 6 months followed by 2 months without treatment.
23 sty 2023 · A phase II clinical trial investigated whether SFN could lead to a decline of ≥ 50% in Prostate Specific Antigen (PSA) levels in prostate cancer patients. Twenty participants were treated with 200 μmol/day of SFN-rich extracts for a maximum period of 20 weeks and their PSA levels were measured.
16 cze 2023 · Sulforaphane can also be used with conventional cancer treatments to achieve an enhanced effect. The group of Małgorzata Milczarek shed light on the development of new combinations by conducting an in vitro study.
11 lip 2024 · Results of the in vivo experiment showed up to 31% tumor growth inhibition after sulforaphane treatment associated with lowered proliferating potential of cancer cells, reduced areas of...
23 lip 2017 · A double-blinded, randomized, placebo-controlled clinical trial that involved 78 patients with biochemical recurrence of prostate cancer after radical prostatectomy used a daily oral administration of 60 mg of stabilized free SFN for 6 months followed by 2 months without treatment.
10 mar 2020 · It was shown in numerous studies to be active against multiple cancer types including pancreatic, prostate, breast, lung, cervical, and colorectal cancers. Sulforaphane exerts its therapeutics action by a variety of mechanisms, such as by detoxifying carcinogens and oxidants through blockage of phase I metabolic enzymes, and by arresting cell ...
