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Pyrimethamine is an antiparasitic drug. It prevents the growth and reproduction of parasites. Sulfadoxine is a sulfa drug that fights bacteria in the body. The combination of pyrimethamine and sulfadoxine is used to treat malaria, a disease caused by parasites.
The combination is considered to be more effective in treating malaria caused by Plasmodium falciparum than that caused by P. vivax, for which chloroquine is considered more effective, though in the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine combination may be indicated. [7]
7 wrz 2024 · Detailed drug Information for Pyrimethamine and sulfadoxine. Includes common brand names, drug descriptions, warnings, side effects and dosing information.
Pyrimethamine/ sulfadoxine is used for: Treating and preventing malaria when other medicines (eg, chloroquine) are not effective or appropriate. Pyrimethamine/sulfadoxine is an antimalarial agent. It works by blocking the formation of folinic acid within the malaria organism, which kills the parasite.
19 sty 2017 · Fansidar (sulfadoxine and pyrimethamine) is an antimalarial agent, each tablet containing 500 mg N 1-(5,6-dimethoxy-4-pyrimidinyl) sulfanilamide (sulfadoxine) and 25 mg 2,4-diamino-5-(p-chlorophenyl)-6-ethylpyrimidine (pyrimethamine).
30 cze 2007 · Sulfadoxine is used in combination with pyrimethamine for the treatment or prevention of malaria. It can also be used to treat various infections in livestock as well. Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in those patients in whom chloroquine resistance is suspected.
Sulfadoxine (also spelled sulphadoxine) is an ultra-long-lasting sulfonamide used in combination with pyrimethamine to treat malaria. [1] It is also used to prevent malaria [2] but due to high levels of sulphadoxine-pyrimethamine resistance, this use has become less common. [3]