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STRUKTUR HIV. HIV merupakan virus RNA berbentuk sferis dengan diameter 100 nm, terdiri dari bagian inti (core) berbentuk silindris dan dikelilingi oleh selubung (envelope) sehingga virus ini peka terhadap inaktivasi.
16 mar 2012 · Here, we review recent advances in HIV-1 structural biology, focusing on the molecular mechanisms of viral replication and on the development of new therapeutics. Schematic overview of the...
HIV-1 arose through several independent zoonotic transmissions of simian immunodeficiency viruses during the last century 1–3. Today, HIV-1, along with its less widespread cousin HIV-2, infects over 30 million people worldwide.
The most relevant naturally occurring methylxanthines are caffeine (1,3,7-trimethylxanthine), theophylline (1,3-dimethylxanthine) and theobromine (3,7-dimethylxanthine). Paraxanthine (1,7-dimethylxanthine), an isomer of theobromine and theophylline, is not produced by plants but is the major dimethylated byproduct of caffeine.
Using these data, researchers have designed new treatments for HIV infection, including effective drug regimens that halt the growth of the virus. The structures also provide new hope for development of a vaccine. Click anywhere on the virus or choose a protein from the menu to beging exploring.
16 mar 2012 · Key Points. HIV-1 replication relies on the proper functioning of specific viral proteins, three of which — protease, integrase, and reverse transcriptase with associated RNase H activity — are...
Breakthroughs in the prevention of HIV important to public health include male medical circumcision, antiretrovirals to prevent mother-to-child transmission, antiretroviral therapy in people with HIV to prevent transmission, and antiretrovirals for pre-exposure prophylaxis.