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STRUKTUR HIV. HIV merupakan virus RNA berbentuk sferis dengan diameter 100 nm, terdiri dari bagian inti (core) berbentuk silindris dan dikelilingi oleh selubung (envelope) sehingga virus ini peka terhadap inaktivasi.
16 mar 2012 · Here, we review recent advances in HIV-1 structural biology, focusing on the molecular mechanisms of viral replication and on the development of new therapeutics. Schematic overview of the...
10 maj 2024 · Human immunodeficiency virus type 1 (HIV-1) remains a serious health threat in Indonesia. In particular, the CRF01_AE viruses were the predominant HIV-1 strains in various cities in...
16 mar 2012 · Key Points. HIV-1 replication relies on the proper functioning of specific viral proteins, three of which — protease, integrase, and reverse transcriptase with associated RNase H activity —...
29 sty 2021 · The capsid (CA) protein of the human immunodeficiency virus type 1 (HIV-1) is an essential structural component of a virion and facilitates many crucial life cycle steps through interactions...
key components of the lentivirus HIV -1, including the envelope glycoproteins, the capsid and the replication enzymes reverse transcriptase, integrase and protease, have been scrutinized to...
Structure of the virion. HIV-1 virions contain two copies of a single-stranded RNA genome within a conical capsid surrounded by a plasma membrane of host-cell origin containing viral envelope proteins. The RNA genome is 9750 nucleotides long (Ratner et al., 1985; Wain-Hobson, 1989), and the virions measure approximately 120 nm in diameter.