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  1. 8 sie 2023 · Streptococcus pneumoniae is a gram-positive, lancet-shaped bacterium and a cause of community-acquired pneumonia. Pneumococcal infections are present throughout the world and are most prevalent during the winter and early spring months.

  2. 13 maj 2012 · In this study of patients with community-acquired Streptococcus pneumoniae bacteremia (SPB), 60 % had severe sepsis or septic shock at the time of hospital arrival. The overall 30-day mortality rate was 16 %, and it was highest among male patients, patients with nosocomial infection, and increased with age, more comorbidity, and with severity ...

  3. 12 mar 2024 · Streptococcus pneumoniae (pneumococcus) has long been one of the most prominent bacterial causes of disease in humans and was one of the first to be identified as a cause of human infection . Since 2000, however, its impact has been blunted by the widespread use of vaccines that largely prevent infection and colonization in young children.

  4. Sepsis-causing bacteria overcome this mechanism of human innate immunity by versatile respiration, production of antioxidant enzymes, hemolysins, exo- and endotoxins, exopolymers and other factors that suppress host defense and provide bacterial survival.

  5. 5 mar 2023 · Streptococcus pneumoniae (Spn) is a major public health problem, as it is a main cause of otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis. Acute episodes of pneumococcal disease have been demonstrated to cause organ damage with lingering negative consequences.

  6. Streptococcus pneumoniae is the main cause of community acquired pneumonia and meningitis in children and the elderly, [5] and of sepsis in those infected with HIV. The organism also causes many types of pneumococcal infections other than pneumonia.

  7. 28 lis 2023 · Pneumococcal diseases are symptomatic infections caused by the bacterium Streptococcus pneumoniae (S. pneumoniae), commonly referred to as pneumococci. The term invasive pneumococcal disease (IPD) is used for more severe and invasive pneumococcal infections, such as bacteraemia, sepsis, meningitis and osteomyelitis, in which the bacterium can ...

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