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How does thermostatic steam trap operation afect the occurrence of temperature validation faults? What new technologies are available to mitigate common SIP problems? Specific answers to these questions will be covered in this white paper.
A good understanding of basic steam sterilization principles and cycles is necessary to avoid mistakes that can lead to non-sterile load items, poor performance of the equipment, personnel injury, lower productivity, higher operation and maintenance costs, and damage to load items.
Steam-in-Place (SIP), the Problems and a New Solution. Validation engineers face many challenges when validating steam-in-place or sterilization-in-place (SIP) systems. Of great concern is the loss of biological indicators within the expanse of process piping during validation.
Important notes: The potential for contamination introduced downstream of a particular point. Ex:, components after POU valves, such as hoses, gaskets or heat exchangers. Chemical contamination in sub-loops, parallel loops or other portions of the system could affect only that portion.
Armstrong's Best Practices Piping Diagrams for Steam and Condensate Systems. Steam Trap Location Points. Steam Main Header. condensate drain points with traps. Saturated Steam: Every 150-300 feet (25-50 m) Superheated Steam: Every 300-500 (50-75 m) Steam Valve Station Drainage. Install steam traps before normally closed manual valves, pressure.
Effective steam sterilization is reliant on good quality steam. This SOP is to provide test procedures to monitor the quality of the steam at the clean steam generator and points
