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2 sty 2018 · The selective serotonin reuptake inhibitors (SSRIs) are the most extensively studied of the newer antidepressants and are increasingly being used as first-line treatment for depression (Anderson et al, 2000). In this article we concentrate on issues that need to be taken into account when selecting one of the five SSRIs marketed in the UK ...
SSRIs are generally well tolerated in patients less than 18 years of age and the majority of adverse reactions (TEAEs) during treatment are mild or moderate. In most RCTs evaluating the efficacy of SSRIs in depression in patients <18 years of age, rates of suicidal ideation or the
1 maj 2023 · Selective serotonin reuptake inhibitors (SSRIs) are a class of medications most commonly prescribed to treat depression. They are often used as first-line pharmacotherapy for depression and numerous other psychiatric disorders due to their safety, efficacy, and tolerability.
Procedure template. Purpose. The purpose of this guidance is to advise clinicians about strategies to swap or stop antidepressants in primary or secondary care. It is a guide only and does not replace clinical judgement or a thorough assessment of the individual circumstances.
SUMMARY. Switching from one antidepressant to another is frequently indicated due to an inadequate treatment response or unacceptable adverse effects. All antidepressant switches must be carried out cautiously and under close observation.
Selective Serotonin Reuptake Inhibitors (SSRIs) neuropathic pain associated with chemotherapy, diabetes, and fibromyalgia. Elderly: sertraline, citalopram, and escitalopram are the preferred agents. Paroxetine should not be used to due heavy anticholinergic activity.
Consider SSRIs when depression, or anxiety disorder is moderate to severe, interferes with daily activities of living, participation in psychotherapy, or when patient has limited improvement despite engaging in psychotherapy.