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The author explores the reasons for the different profiles and discusses adverse effects, especially sexual dysfunction, weight gain, and sleep disturbance, the most troubling adverse events seen during long-term SSRI therapy. The informed management of these side effects by primary care practitioners supports successful treatment of depression.
1 maj 2023 · Common side effects from SSRIs include sexual dysfunction, sleep disturbances, weight changes, anxiety, dizziness, xerostomia, headache, and gastrointestinal distress. SSRIs also have the potential to prolong the QT interval, which can lead to fatal arrhythmia, torsade de pointes.
Sexual side effects are common with most antidepressants. Bupropion and mirtazapine may be least problematic. Many antidepressants are substrates of CYP450 enzymes. See our Cytochrome P450 Drug Interactions chart to help check for interactions. --absent or rare to ++++ relatively common.
This table shows which side effects are seen with different antidepressants. The more dots there are, the more important a side effect is: No dots: None; 1 dot ( ): Slight; 2 dots ( ): Low; 3 dots ( ): Moderate; 4 dots ( ): High
The most common side effects of SSRIs are nausea, headaches, decreased sex drive, and feeling “jittery.” Some patients also have noticed fatigue and difficulty sleeping. Many side effects go away after taking the medication consistently for 1-2 weeks.
8 sie 2023 · However, SNRIs can produce anticholinergic-like effects (which appear to be mediated by noradrenergic stimulation) such as dry mouth and constipation, and they should be used with caution in narrow angle glaucoma.
SSRI Side Effects and Management strategies. If side effects occur, they are most notable during the initial 4 weeks of titrating the dose. . 2. How to talk to families about Black-box warnings and side effects . Parent: Is my child/teen more likely to hurt and kill themself being on an antidepressant?
