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The influenza pandemic of 1918 killed more than 50 million people worldwide. In addition, its socioeconomic consequences were huge. “Spanish flu”, as the infection was dubbed, hit different age-groups, displaying a so-called “W-trend”, typically with two spikes in children and the elderly.
12 paź 2010 · The Spanish flu pandemic of 1918-1919 was the deadliest pandemic in world history, infecting some 500 million people across the globe—roughly one-third of the population—and causing up to 50...
Early attempts at a vaccine during the 1918 influenza pandemic were based on this understanding, and it was not until the 1930s, when the influenza virus was identified, that progress towards an effective vaccine could really begin.
However, vaccines against these very small agents, which they called viruses, had already been developed going back to the smallpox vaccine in late eighteenth century. Richard Shope, who demonstrated that the 1918 pandemic was caused by a virus, and connected the human and swine flu viruses.
27 wrz 2017 · We call that tidal wave the Spanish flu, and many things changed in the wake of it. One of the most profound revolutions took place in the domain of public health.
The Spanish “origin” relates to reports in the press of cases of influenza in the summer of 1918, where as many as eight million Spaniards succumbed to the disease. Even the King of Spain, Alfonso XIII, caught influenza in 1918.
The 1918 “Spanish flu” pandemic was caused by a founder H1N1 influenza A virus. The three subsequent pandemics of 1957, 1968, and 2009 (black arrows) were caused by descendants of the 1918 virus, which acquired one or more genes through reassortment ( 12 ).
