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In most smooth muscles, PKC has contraction-promoting effects such as phosphorylation of Ca 2+ channels or other proteins that regulate cross-bridge cycling. Activator Ca 2+ binds to calmodulin, leading to activation of myosin light chain kinase (MLC kinase).
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SMOOTH MUSCLE CONTRACTION AND RELAXATION R. Clinton Webb...
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Chętnie wyświetlilibyśmy opis, ale witryna, którą oglądasz,...
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Exercise offers a unique stage from which to study and teach...
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Smooth muscle displays involuntary control and can be triggered via hormones, neural stimulation by the ANS, and local factors. In certain locations, such as the walls of visceral organs, stretching the muscle can trigger its contraction).
14 sie 2023 · The primary function of smooth muscle is contraction. Smooth muscle consists of two types: single-unit and multi-unit. Single-unit smooth muscle consists of multiple cells connected through connexins that can become stimulated in a synchronous pattern from only one synaptic input.
1 kwi 2023 · General Mechanism of Smooth Muscle Contraction. The contraction of smooth muscle is not regulated by the binding of Ca to the troponin complex, as is seen in cardiac and skeletal muscle contraction. Smooth muscle instead utilizes calmodulin, an intracellular second messenger that binds calcium.
Smooth muscle cells (SMC) make up the muscular portion of the gastrointestinal (GI) tract from the distal oesophagus to the internal anal sphincter. Coordinated contractions of these cells produce the motor patterns of GI motility.
30 lip 2022 · The triggers for smooth muscle contraction include hormones, neural stimulation by the ANS, and local factors. In certain locations, such as the walls of visceral organs, stretching the muscle can trigger its contraction (the stretch-relaxation response).
Smooth muscle contraction is a calcium-dependent process that can be induced by electromechanical coupling (triggered by action potentials and depolarization of the cell membrane) or by pharmacomechanical coupling (receptor-mediated activation of intracellular mechanisms).
