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  1. Cigarette smoking is a major preventable risk factor for lung cancer, contributing to lung cancer progression and metastasis. Moreover, cigarette smoking correlates with increased metastasis frequency of pancreatic, breast and bladder cancer.

  2. 9 lip 2014 · In this review of the literature, the authors demonstrate that CS induces a more malignant tumor phenotype by increasing proliferation, migration, invasion, and angiogenesis and by activating prosurvival cellular pathways.

  3. The figure depicts the major established pathways of cancer causation by cigarette smoking: (1) the exposure to carcinogens (cancer-causing substances), (2) the formation of covalent bonds between the carcinogens and DNA (DNA adduct formation), and (3) the resulting accumulation of permanent somatic mutations in critical genes (genes appear in ...

  4. The impact of smoking on cancer treatment efficacy and toxicity regardless of cancer type was investigated in this meta-analysis. Smoking during radiotherapy/chemoradiotherapy was associated with worse outcomes and a higher risk for toxicity.

  5. In this Review we discuss the known biological effects of smoking on cancer cell biology and emphasise the clinical effects of continued smoking in patients with cancer treated with chemotherapy or radiotherapy.

  6. 17 wrz 2024 · Smoking can cause cancer almost anywhere in the body. Quitting smoking lowers the risk for 12 different cancers and also benefits people diagnosed with cancer. Cancer refers to diseases in which cells divide out of control. These cells can invade or spread to other parts of the body.

  7. This section describes studies examining the effect of tobacco smoke on cancer cells; most of the studies were performed in vitro with cancer cells exposed to tobacco smoke extract or individual tobacco smoke chemical compounds and may not reflect in vivo occurrences.

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