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2 wrz 2022 · First, we investigated the association between smoking-related phenotypes (lifetime amount of smoking, and ever having smoked regularly) and subsequent endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) and UK Biobank.
Summary. Epidemiological studies have shown that cigarette smoking is associated with a reduced risk of endometrial cancer, in contrast to the increased risks observed with many other non-respiratory-tract cancers, including those of the bladder, pancreas, and cervix uteri.
The consistency of risk estimates across strata of endometrial carcinoma risk factors may indicate that cigarette smoking lowers endometrial carcinoma risk through a common mechanism regardless of other characteristics related to endometrial carcinogenesis.
In the premenopausal group, women currently exposed to tobacco smoke either by active or passive smoking has a non significant increased risk of endometrial cancer (HR = 1.56, 95% CI = 0.82–3.03 for active current smokers and HR = 1.31, 95% CI = 0.74–2.34 for passive smokers).
1 lut 2014 · The cigarette smoking–endometrial carcinoma risk relationship was consistent within strata of important endometrial carcinoma risk factors and by clinically relevant tumor characteristics. The inverse relationship between cigarette smoking and endometrial carcinoma risk is well established.
7 maj 2002 · We found that a reduced endometrial cancer risk was evident only among women who currently smoked 20 cigarettes per day or more (hazard ratio=0.62, 95% CI=0.42–0.92, P for trend=0.03)....
Ever smoking was statistically significantly associated with a reduced risk of endometrial cancer among prospective studies (relative risk 0.81; 95% confidence interval [CI], 0.74-0.88) and case-control studies (odds ratio 0.72; 95% CI, 0.66-0.79).
