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  1. Explain the sliding filament process of muscle contraction. Each skeletal muscle is an organ that consists of various integrated tissues. These tissues include the skeletal muscle fibers, blood vessels, nerve fibers, and connective tissue. Each skeletal muscle has three layers of connective tissue (called mysia) that enclose it, provide ...

  2. The process of muscle contraction begins at the site where a motor neuron’s terminal meets the muscle fiber—called the neuromuscular junction (NMJ). Every skeletal muscle fiber in every skeletal muscle is innervated by a motor neuron at a NMJ.

  3. The Mechanism of Muscle Contraction: Sarcomeres, Action Potential, and the Neuromuscular Junction

  4. When signaled by a motor neuron, a skeletal muscle fiber contracts as the thin filaments are pulled and then slide past the thick filaments within the fiber’s sarcomeres. This process is known as the sliding filament model of muscle contraction (Figure 10.10).

  5. Control of Skeletal Muscle Contractions. 1. Muscle contraction begins when an action potential reaches the synaptic terminal of a motor neuron. The neurotransmitter acetylcholine (ACh) is then released into the synaptic cleft of the neuromuscular junction.

  6. Compare action potential s of muscle and nerve. Explain the aspects of muscle contraction that dictate energy cost. Describe the location and function of various calcium handling proteins in muscle. Draw a diagram illustrating the activation of muscle including calcium handling.

  7. Learning Objectives. After reading this section, you should be able to- Define the following terms: tension, contraction, twitch, motor unit, and myogram. Interpret a myogram of a twitch contraction with respect to the duration of the latent, contraction, and relaxation periods and describe the events that occur in each period.

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